Turkish Journal of Surgery

Turkish Journal of Surgery

ISSN: 2564-6850
e-ISSN: 2564-7032


Sefa Ergün1 , Ozan Akıncı1, Tülin Öztürk2, Adem Karataş1

1Department of General Surgery, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey
2Department of Clinical Pathology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey


Hyalinizing trabecular tumor was first described by Carney et al. (1) in 1987 and is a rare benign tumor of the thyroid gland that shares some of the microscopic features of medullary and papillary thyroid carcinoma. Hyalinizing trabecular tumor derives from follicular cells, and it is characterized by an apparent trabecular pattern and intratrabecular hyalinization. In this study, we present the case of a 40-year-old female patient with thyroid gland nodules, whose ultrasound results, clinical behavior, and fine-needle aspiration biopsy results were suspicious; the pathology after thyroidectomy indicated hyalinizing trabecular tumor. We aimed to show the role of clinical behavior, radiology, fine-needle aspiration, and histological and immunohistochemical analysis in the differential diagnosis of hyalinizing trabecular tumor. Hyalinizing trabecular tumor which can be confused with papillary and medullar carcinoma of the thyroid gland, is mostly benign but some malignant and metastatic cases have been reported. Therefore, diagnosis, treatment, and follow-up steps of Hyalinizing trabecular tumor should be planned in consideration of a malignant potential.

Keywords: Thyroid tumors, hyalinizing trabecular tumor, trabecular pattern

Cite this paper as: Ergün S, Akıncı O, Öztürk T, Karataş A. Hyalinizing trabecular tumor of the thyroid gland. Turk J Surg 2018; 34: 149-151.


Peer Review

Externally peer-reviewed.

Author Contributions

Concept -S.E., A.K.; Design - S.E., O.A.; Supervision - A.K., T.Ö.; Resource - S.E., O.A.; Materials - S.E., O.A., T.Ö.; Data Collection and/or Processing - S.E., O.A., T.Ö.; Analysis and/or Interpretation - T.Ö., A.K.; Literature Search - S.E., O.A.; Writing Manuscript - S.E., O.A.; Critical Reviews - T.Ö., A.K.

Conflict of Interest

The authors have no conflicts of interest to declare.

Financial Disclosure

The authors declared that this study has received no financial support.