Turkish Journal of Surgery

Turkish Journal of Surgery

ISSN: 2564-6850
e-ISSN: 2564-7032


Cengiz Tavusbay, Turan Acar, Haldun Kar, Kemal Atahan, Erdinç Kamer

Department of General Surgery, İzmir Katip Çelebi University Training and Research Hospital, İzmir, Turkey


Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by mucocutaneous hyperpigmentation, and intestinal and extraintestinal multiple hamartomatous polyps. Development of gastrointestinal and extragastrointestinal cancer risk is markedly increased in patients with Peutz-Jeghers syndrome. We analyzed five patients from two families diagnosed with Peutz-Jeghers syndrome between 1999 and 2012. This study confirms the actual malignancy potency of PJS. Therefore, we suggest a close follow-up of patients with Peutz-Jeghers syndrome for the risk of malignancy.

Keywords: Peutz-Jeghers syndrome, hamartomatous polyp, intussusception

This study was presented at the 18th National Surgical Congress, 23-27 May 2012, İzmir, Turkey.
Cite this paper as: Tavusbay C, Acar T, Kar H, Atahan K, Kamer E. The patients with Peutz-Jeghers syndrome have a high risk of developing cancer. Turk J Surg 2018; DOI: 10.5152/turkjsurg.2017.3241


Peer Review


Author Contributions

Concept - C.T., T.A., H.K.; Design - C.T., T.A.; Supervision - K.A., E.K.; H.K.; Resource - C.T., T.A.; Materials - C.T., H.K., E.K.; Data Collection and/or Processing - C.T., T.A.; Analysis and/or Interpretation - K.A., E.K.; H.K.; Literature Search - C.T., T.A.; Writing Manuscript - C.T., T.A.; Critical Reviews - K.A., E.K., H.K.

Conflict of Interest

The authors have no conflicts of interest to declare.

Financial Disclosure

The authors declared that this study has received no financial support.