THE EFFECTS OF INTRAPERITONEAL LAVAGE SOLUTIONS IN BARIUM PERITONITIS
ÖMER ALABAZ1, CANAN ERSÖZ2, EMİN U ERKOÇAK1, HALUK DEMİRYÜREK1, NAZAN ALPARSLAN3, MELEK ERGİN2
1Çukurova Üniversitesi Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Balcalı, ADANA
2Çukurova Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Balcalı, ADANA
3Çukurova Üniversitesi Tıp Fakültesi, Halk Sağlığı Anabilim Dalı, Balcalı, ADANA
Abstract
An experimental model of established barium peritonitis in the rat was used to test the effect of various peritoneal lavage solutions with systhemic agents on survival. This experimental study was made on 70 Wistar-Albino rats divided in 3 groups:
1. Group: in the first group (control group) including 10 rats, established barium peritonitis were not given any treatment. Mortality rate was 100%.
2. Group: After establishing barium peritonitis, agents were given intraperitoneally during the first 2 hours in the second (early treatment) group, it was divided in three subgroups:
2a: Serum saline was used. Mortality rate was 40%
2b: Metranidazole was used. Mortality rate was 30%
2c: Povidon-iodine was used. Mortality rate was 70%
3. Group: After establishing barium peritonitis, agents were given intraperitoneally 24 hours later in the third group (late treatment). It was divided in three subgroups:
3a: Serum saline was used. Mortality rate was 80%
3b: Metranidazole was used. Mortality rate was 50%,
3c; Povidon-iodine was used. Mortality rate was 90%.
We assessed our results according to Fisher exact and chi square test. In comparison of the subgroups, no statistical significance was found. Comparing the second and third groups, second group was found to be statistically significant in mortatity rate.
Keywords: BARIUM, PERITONITIS, MORTALITY, PERITONEAL LAVAGE SOLUTION