Erectile dysfunction after surgery for rectal cancer: A prospective study
Aylin Hande Gökçe1, Hakan Özkan2
1Clinic of General Surgery, Istanbul Medicine Hospital, Istanbul, Turkey
2Clinic of General Surgery, Star Medica Hospital, Tekirdag, Turkey
Objective: Erectile dysfunction may occur as a complication of surgical treatment of rectal cancer in male patients. We compared the rates of postoperative erectile dysfunction and response to medical treatment after low anterior resection (LAR) and Miles’ procedures.
Material and Methods: Fifty patients who underwent the Miles’ procedure or LAR were prospectively assessed. This study includes fifty patients with stages 1 and stage 2 rectal cancer based on clinical and radiologic assessments, who underwent Miles’ (25 out of 50 patients underwent the Miles’procedure and ) or LAR (25 patients underwent LAR) procedures were prospectively assessed. The International Index of Erectile Function (IIEF) form was, used in the assessment to assess erectile dysfunction. This questionnaire, was administered preoperatively and 6 months postoperatively. For the patients with IIEF scores ≤ 25 at postoperative 6th months, tadalafil 5 mg is was given for 12 weeks and IIEF is was repeated after then.
Results: No significant differences were found in mean IIEF scores preoperatively (p= 0.695). In both groups, IIEF scores were significantly lower postoperatively compared with preoperatively (p= 0.00001, LAR; p= 0.00001, Miles’). Mean postoperative IIEF scores were significantly lower in patients who underwent Miles’ compared with the LAR procedures (p= 0.0001). For patients with IIEF scores ≤ 25 at 6 months, tadalafil 5 mg was given for 12 weeks and IIEF scores were better in both groups (p= 0.00001).
Conclusion: The erectile dysfunction rate after Miles’ procedure was significantly higher than the rate of patients who developed erectile dysfunction after LAR surgery. We tried to emphasize that in after LAR surgery. We should not be concerned only with cancer treatment surgically in rectal tumour patients, but remember that situations affecting their social life, such as postoperative erectile dysfunction, have medical and psychologic importance.
Keywords: Erectile dysfunction, rectal cancer, rectal tumors, colorectal surgery
Cite this article as: Gökçe AH, Özkan H. Erectile dysfunction after surgery for rectal cancer: A prospective study. Turk J Surg 2019
Authors declared that the research was conducted in accordance with the principles of the World Medical Association Declaration of Helsinki “Ethical Principles for Medical Research Involving Human Subjects”. Ethics approval for this study was obtained from the Ethics Committee (KAEK-50-1345).
Written informed consent was obtained from patients who participated in this study.
Consept - A.H.G., H.Ö.; Design - A.H.G., H.Ö.; Supervision - A.H.G., H.Ö.; Resource - A.H.G., H.Ö.; Materials - A.H.G., H.Ö.; Data Collection and/or Processing - A.H.G., H.Ö.; Analysis and Interpretation - A.H.G., H.Ö.; Literature Search - A.H.G., H.Ö.; Writing Manuscript - A.H.G., H.Ö.; Critical Reviews - A.H.G., H.Ö.
The authors have no conflicts of interest to declare.
The authors declared that this study has received no financial support.
I would like to thank to MD Associate professor Dr. Acar Aren for his kind acknowledgements to our paper.