Turkish Journal of Surgery

Turkish Journal of Surgery

ISSN: 2564-6850
e-ISSN: 2564-7032


Abdullah Durhan1, Gamze Durhan2, Aydan Eroğlu1

1Department of General Surgery and Surgical Oncology, Ankara University School of Medicine, Ankara, Turkey
2Department of Radiology, Ankara Training and Research Hospital, Ankara, Turkey


The neutrophil-to-lymphocyte ratio is clinically accepted as a marker of systemic inflammatory response. In breast cancer patients, neutrophil-to-lymphocyte ratio can be used as an important prognostic indicator of survival. In routine laboratory tests, the platelet-to-lymphocyte ratio can also be examined in addition to neutrophil-to-lymphocyte ratio. Although the effects on breast cancer survival of platelet-to-lymphocyte ratio, which is accepted as the twin of neutrophil-to-lymphocyte ratio, are not as widely accepted as those of neutrophil-to-lymphocyte ratio, platelet activation is known to be a feature of cancer. Here, we present the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio of a patient with locally advanced cancer of the left breast who underwent a simple mastectomy that reduced the tumor load. Following surgical therapy, a remarkable regression was observed in the local recurrence area of the right mastectomy site; at the same time, the patient’s neutrophil-to-lymphocyte ratio and PLR values significantly decreased.

Keywords: Locally advanced stage, breast cancer, simple mastectomy, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio

Cite this paper as: Durhan A, Durhan G, Eroğlu A. Regression in local recurrence in the contralateral breast following mastectomy in bilateral locally advanced breast cancer: a comparison of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios. Turk J Surg 2018; 34: 140-142.


Peer Review

Externally peer-reviewed.

Author Contributions

Concept - A.D., A.E.; Design - A.D., G.D., A.E.; Supervision - A.E.; Resource A.D., A.E.; Materials - A.D., A.E.; Data Collection and/or Processing - A.D., G.D., A.E.; Analysis and/or Interpretation - A.D., G.D., A.E.; Literature Search - A.D., G.D., A.E.; Writing Manuscript - A.D., G.D., A.E.; Critical Reviews - A.D., G.D., A.E.

Conflict of Interest

The authors have no conflicts of interest to declare.

Financial Disclosure

The authors declared that this study has received no financial support.