Turkish Journal of Surgery

Turkish Journal of Surgery

ISSN: 2564-6850
e-ISSN: 2564-7032

 

Turan Acar1, Ercüment Tarcan1, Mehmet Hacıyanlı1, Erdinç Kamer1, Mustafa Peşkersoy1, Seyran Yiğit2, Özlem Gür1, Necat Cin1, Ayşegül Akder Sarı2, Fatma Tatar1

Abstract

Objective: Phyllodes tumor of the breast is a rare fibroepithelial breast tumor that comprise 0.3-0.9% of primary breast neoplasms. In this study, we aimed to present clinicopathologic symptoms of our patients along with their treatment modality.
Material and Methods: Clinicopathologic properties and treatment modality of 20 phyllodes patients who underwent surgery between January 2008 and January 2013 were retrospectively evaluated.
Results: Median patient age was 46.55 years (22-75). Fine-needle aspiration biopsy was applied to 19 patients. Biopsy results were reported as suspicious in four, malignant in three, benign in 11, and as non-diagnostic in one patient. Final histopathology reports revealed two benign, one malignant and one borderline tumor out of the four patients with suspicious findings on fine needle aspiration biopsy; all patients with malignant cytology had malignancy. There were two borderline and nine benign lesions within the benign biopsy group. Sixteen patients underwent segmental mastectomy, four patients underwent mastectomy with/without axillary dissection. The median tumor size was 6 (1-13) cm. Histopathologically, 11 (55%) tumors were benign, 5 (25%) were borderline, and 4 (20%) were malignant. Two of the four patients with malignancy underwent radiotherapy and chemotherapy, and one patient only received chemotherapy as adjuvant treatment.
Conclusion: Phyllodes tumors are rare, mix-type breast tumors. Due to high rates of local recurrence and potential for malignancy, preoperative diagnosis and accurate management are important.

Keywords: Phyllodes tumor, breast cancer, mastectomy


 

Ethics Committee Approval

Ethics committee approval was received for this study from the ethics committee of İzmir Katip Çelebi University Atatürk Training and Research Hospital (Decision number: 168; Date: 02.08.2013).

Peer Review

Externally peer-reviewed.

Author Contributions

Concept - T.A., E.T., M.H., E.K., M.P., S.Y., Ö.G., N.C., A.A.S., F.T.; Design - T.A., E.T., M.H., E.K., M.P., S.Y., Ö.G., N.C., A.A.S., F.T.; Supervision - T.A., E.T., M.H., E.K., M.P., S.Y., Ö.G., N.C., A.A.S., F.T.; Funding - T.A., E.T.; Materials - T.A., S.Y., A.A.S.; Data Collection and/or Processing - T.A., E.K.; Analysis and/or Interpretation - T.A., E.T., M.H., E.K., M.P., S.Y., Ö.G., N.C., A.A.S., F.T.; Literature Review - T.A., E.T., M.H., E.K., M.P., S.Y., Ö.G., N.C., A.A.S., F.T.; Writer - T.A.; Critical Review - M.H., M.P.

Conflict of Interest

No conflict of interest was declared by the authors. 


Financial Disclosure

The authors declared that this study has received no financial support.