Unresectable pancreatic adenocarcinoma with full clinical response following chemoradiotherapy
Erol Aksoy, Murat Ulaş, Muhammet Kadri Çolakoğlu, İlter Özer, Erdal Birol Bostancı, Musa Akoğlu
Clinic of Gastroenterology Surgery, Türkiye Yüksek İhtisas Training and Research Hospital, Ankara, Turkey
Abstract
Locally advanced or metastatic disease is present in 2/3s of patients with pancreatic cancer. Pancreatic cancer patients are assessed as resectable, potentially resectable (borderline) and unresectable according to pre-operative examinations. The chance for operability may be enhanced by using adjuvant-neoadjuvant systemic chemotherapy, radiotherapy or both. The rates of R0 resection may be increased by means of treatment delivered this way. This case report presents a pancreatic adenocarcinoma case that was assessed to be resectable but was identified to be unresectable during surgical exploration, thus received adjuvant chemoradiotherapy. The patient was then re-evaluated, identified as resectable and received pancreaticoduodenectomy.
Keywords: Pancreas, adenocarcinoma, resectability, chemotherapy
Written informed consent was obtained from the parents of the patients who participated in this study.
Externally peer-reviewed.
Concept - E.A., M.U., M.K.Ç.; Design - E.A.; Supervision - İ.Ö., E.B.B., M.A.; Funding - E.A.; Materials - M.U.; Data Collection and/or Processing - M.U.; Analysis and/or Interpretation - M.K.Ç., M.A., İ.Ö., E.B.B.; Literature Review - İ.Ö., E.B.B.; Writer - E.A., M.K.Ç.; Critical Review - İ.Ö., E.B.B., M.A.
No conflict of interest was declared by the authors.
The authors declared that this study has received no financial support.